6EAY
Structural Basis for Broad Neutralization of Ebolaviruses by an Antibody Targeting the Glycoprotein Fusion Loop
Summary for 6EAY
Entry DOI | 10.2210/pdb6eay/pdb |
Descriptor | CA45 light chain, CA45 heavy chain, Envelope glycoprotein, ... (6 entities in total) |
Functional Keywords | ebolavirus, glycoprotein, cross-protective antibody, broadly neutralizing antibody, ca45, fusion loop, cross-reactive, filovirus, viral protein |
Biological source | Macaca fascicularis More |
Total number of polymer chains | 4 |
Total formula weight | 104257.06 |
Authors | Janus, B.M.,Ofek, G. (deposition date: 2018-08-03, release date: 2018-10-10, Last modification date: 2023-10-11) |
Primary citation | Janus, B.M.,van Dyk, N.,Zhao, X.,A Howell, K.,Soto, C.,Aman, M.J.,Li, Y.,Fuerst, T.R.,Ofek, G. Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop. Nat Commun, 9:3934-3934, 2018 Cited by PubMed: 30258051DOI: 10.1038/s41467-018-06113-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.72 Å) |
Structure validation
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