6E59
Crystal structure of the human NK1 tachykinin receptor
Summary for 6E59
Entry DOI | 10.2210/pdb6e59/pdb |
Descriptor | Substance-P receptor, GlgA glycogen synthase, Substance-P receptor chimera, 1-(4-{[(2R,3S)-2-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholin-4-yl]methyl}-1H-1,2,3-triazol-5-yl)-N,N-dimethylmethanamine (2 entities in total) |
Functional Keywords | g protein-coupled receptor fusion protein, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 1 |
Total formula weight | 62449.70 |
Authors | Yin, J.,Clark, L.,Chapman, K.,Shao, Z.,Borek, D.,Xu, Q.,Wang, J.,Rosenbaum, D.M. (deposition date: 2018-07-19, release date: 2018-12-12, Last modification date: 2023-10-11) |
Primary citation | Yin, J.,Chapman, K.,Clark, L.D.,Shao, Z.,Borek, D.,Xu, Q.,Wang, J.,Rosenbaum, D.M. Crystal structure of the human NK1tachykinin receptor. Proc. Natl. Acad. Sci. U.S.A., 115:13264-13269, 2018 Cited by PubMed: 30538204DOI: 10.1073/pnas.1812717115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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