6DK0
Human sigma-1 receptor bound to NE-100
Summary for 6DK0
Entry DOI | 10.2210/pdb6dk0/pdb |
Descriptor | Sigma non-opioid intracellular receptor 1, N-{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl}-N-propylpropan-1-amine, SULFATE ION, ... (6 entities in total) |
Functional Keywords | membrane protein, antagonist bound, receptor, sigma-1 receptor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 81883.66 |
Authors | Schmidt, H.R.,Kruse, A.C. (deposition date: 2018-05-28, release date: 2018-10-17, Last modification date: 2023-10-11) |
Primary citation | Schmidt, H.R.,Betz, R.M.,Dror, R.O.,Kruse, A.C. Structural basis for sigma1receptor ligand recognition. Nat. Struct. Mol. Biol., 25:981-987, 2018 Cited by PubMed: 30291362DOI: 10.1038/s41594-018-0137-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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