6DK0
Human sigma-1 receptor bound to NE-100
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Sigma non-opioid intracellular receptor 1 | polymer | 227 | 25447.9 | 3 | UniProt (Q99720) Pfam (PF04622) In PDB | Homo sapiens (Human) | Aging-associated gene 8 protein,SR31747-binding protein,SR-BP,Sigma 1-type opioid receptor,hSigmaR1 |
| 2 | A, B, C | N-{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl}-N-propylpropan-1-amine | non-polymer | 355.5 | 3 | Chemie (GKY) | |||
| 3 | A, B, C | SULFATE ION | non-polymer | 96.1 | 14 | Chemie (SO4) | |||
| 4 | A, B, C | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | C, A | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate | non-polymer | 356.5 | 8 | Chemie (OLC) | |||
| 6 | water | water | 18.0 | 96 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 223 (UniProt: Q99720)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 76343.6 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 5540.0 | |
| All* | Total formula weight | 81883.7 |
