6DBW
Cryo-EM structure of RAG in complex with 12-RSS substrate DNA
Summary for 6DBW
Entry DOI | 10.2210/pdb6dbw/pdb |
Related | 6DBI 6DBJ 6DBL 6DBO 6DBQ 6DBR 6DBU 6DBV 6DBW 6DBX |
EMDB information | 7843 7844 7845 7846 7847 7848 7849 7850 7851 7852 7853 |
Descriptor | Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward strand of 12-RSS substrate DNA, ... (6 entities in total) |
Functional Keywords | v(d)j recombination, rag complex, melted rss substrate, pre-cleveage complex, singly-bound complex, recombination-dna complex, recombination/dna |
Biological source | Escherichia coli More |
Total number of polymer chains | 6 |
Total formula weight | 412287.84 |
Authors | |
Primary citation | Ru, H.,Mi, W.,Zhang, P.,Alt, F.W.,Schatz, D.G.,Liao, M.,Wu, H. DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25:732-742, 2018 Cited by PubMed: 30061602DOI: 10.1038/s41594-018-0098-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.7 Å) |
Structure validation
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