6D01

Crystal structure of 1210 Fab in complex with circumsporozoite protein NANP5

Summary for 6D01

Entry DOI	10.2210/pdb6d01/pdb
Descriptor	1210 Antibody, heavy chain, 1210 Antibody, Light chain, NANP5, ... (5 entities in total)
Functional Keywords	malaria, antibody, circumsporozoite protein, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	10
Total formula weight	198949.41
Authors	Scally, S.W.,Bosch, A.,Imkeller, K.,Wardemann, H.,Julien, J.P. (deposition date: 2018-04-09, release date: 2018-06-13, Last modification date: 2018-07-04)
Primary citation	Imkeller, K.,Scally, S.W.,Bosch, A.,Marti, G.P.,Costa, G.,Triller, G.,Murugan, R.,Renna, V.,Jumaa, H.,Kremsner, P.G.,Sim, B.K.L.,Hoffman, S.L.,Mordmuller, B.,Levashina, E.A.,Julien, J.P.,Wardemann, H. Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope. Science, 360:1358-1362, 2018 Cited by PubMed: 29880723 DOI: 10.1126/science.aar5304 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation