6D01

Crystal structure of 1210 Fab in complex with circumsporozoite protein NANP5

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue EDO A 301

Chain	Residue
A	LYS56
A	LYS57
A	TYR58

---

site_id	AC2
Number of Residues	3
Details	binding site for residue EDO A 302

Chain	Residue
A	ASP53
A	ARG71
A	ASN73

---

site_id	AC3
Number of Residues	2
Details	binding site for residue EDO A 303

Chain	Residue
A	SER25
A	GLY26

---

site_id	AC4
Number of Residues	5
Details	binding site for residue EDO A 304

Chain	Residue
A	ASP61
A	PEG305
B	ASP1
B	TYR94
A	TYR59

---

site_id	AC5
Number of Residues	5
Details	binding site for residue PEG A 305

Chain	Residue
A	GLU46
A	TRP47
A	ALA60
A	EDO304
B	ASP1

---

site_id	AC6
Number of Residues	7
Details	binding site for residue EDO B 301

Chain	Residue
B	GLN37
B	LYS45
B	LEU47
B	PRO59
B	PHE62
B	ASP81
B	ASP82

---

site_id	AC7
Number of Residues	3
Details	binding site for residue EDO B 302

Chain	Residue
B	SER67
B	THR69
B	EDO306

---

site_id	AC8
Number of Residues	5
Details	binding site for residue EDO B 303

Chain	Residue
B	GLN27
B	SER28
C	EDO301
D	LYS50
F	GLN199

---

site_id	AC9
Number of Residues	1
Details	binding site for residue EDO B 304

Chain	Residue
B	LYS50

---

site_id	AD1
Number of Residues	6
Details	binding site for residue EDO B 305

Chain	Residue
A	LEU141
A	VAL169
A	SER177
A	SER179
B	SER176
B	THR178

---

site_id	AD2
Number of Residues	2
Details	binding site for residue EDO B 306

Chain	Residue
B	SER28
B	EDO302

---

site_id	AD3
Number of Residues	3
Details	binding site for residue EDO B 307

Chain	Residue
B	LYS39
B	LYS42
B	EDO308

---

site_id	AD4
Number of Residues	2
Details	binding site for residue EDO B 308

Chain	Residue
B	LYS42
B	EDO307

---

site_id	AD5
Number of Residues	5
Details	binding site for residue EDO B 309

Chain	Residue
A	GLN39
B	GLN38
B	LYS39
B	GLY41
B	LYS42

---

site_id	AD6
Number of Residues	4
Details	binding site for residue EDO B 310

Chain	Residue
B	ASP1
B	GLN27
B	ASN93
B	EDO311

---

site_id	AD7
Number of Residues	2
Details	binding site for residue EDO B 311

Chain	Residue
B	ASN93
B	EDO310

---

site_id	AD8
Number of Residues	2
Details	binding site for residue PEG B 312

Chain	Residue
B	GLN160
B	GLU161

---

site_id	AD9
Number of Residues	2
Details	binding site for residue PEG B 313

Chain	Residue
B	ARG108
H	EDO304

---

site_id	AE1
Number of Residues	6
Details	binding site for residue EDO C 301

Chain	Residue
B	GLN27
B	ASN92
B	ASN93
B	EDO303
C	SER99
C	ASP100

---

site_id	AE2
Number of Residues	4
Details	binding site for residue EDO C 302

Chain	Residue
C	SER98
C	ASP100
D	TRP32
D	LYS50

---

site_id	AE3
Number of Residues	4
Details	binding site for residue EDO C 303

Chain	Residue
C	GLY44
C	LEU45
C	PEG304
D	GLN100

---

site_id	AE4
Number of Residues	7
Details	binding site for residue PEG C 304

Chain	Residue
C	LEU45
C	GLU46
C	TRP47
C	EDO303
D	TRP96
D	THR97
D	PHE98

---

site_id	AE5
Number of Residues	3
Details	binding site for residue EDO D 301

Chain	Residue
D	SER65
D	GLY66
D	EDO306

---

site_id	AE6
Number of Residues	7
Details	binding site for residue EDO D 303

Chain	Residue
C	LEU141
C	SER177
C	LEU178
C	SER179
D	GLN160
D	SER176
D	THR178

---

site_id	AE7
Number of Residues	3
Details	binding site for residue EDO D 304

Chain	Residue
B	PRO59
B	LEU60
D	GLN155

---

site_id	AE8
Number of Residues	3
Details	binding site for residue EDO D 305

Chain	Residue
D	ARG18
D	SER63
D	PEG309

---

site_id	AE9
Number of Residues	1
Details	binding site for residue EDO D 306

Chain	Residue
D	EDO301

---

site_id	AF1
Number of Residues	1
Details	binding site for residue EDO D 307

Chain	Residue
D	SER67

---

site_id	AF2
Number of Residues	4
Details	binding site for residue EDO D 308

Chain	Residue
D	GLN37
D	LYS45
D	ASP81
D	ASP82

---

site_id	AF3
Number of Residues	3
Details	binding site for residue PEG D 309

Chain	Residue
D	ARG18
D	EDO305
F	PEG309

---

site_id	AF4
Number of Residues	2
Details	binding site for residue EDO E 301

Chain	Residue
E	ASP53
E	ASN73

---

site_id	AF5
Number of Residues	3
Details	binding site for residue EDO E 302

Chain	Residue
E	SER112
E	LEU170
E	TYR176

---

site_id	AF6
Number of Residues	1
Details	binding site for residue EDO E 303

Chain	Residue
E	ARG96

---

site_id	AF7
Number of Residues	1
Details	binding site for residue PEG E 305

Chain	Residue
E	GLU148

---

site_id	AF8
Number of Residues	3
Details	binding site for residue EDO F 301

Chain	Residue
B	GLU143
F	SER26
F	EDO307

---

site_id	AF9
Number of Residues	2
Details	binding site for residue EDO F 302

Chain	Residue
F	SER67
F	THR69

---

site_id	AG1
Number of Residues	6
Details	binding site for residue EDO F 303

Chain	Residue
F	GLN37
F	LYS45
F	PRO59
F	PHE62
F	ASP81
F	ASP82

---

site_id	AG2
Number of Residues	4
Details	binding site for residue EDO F 304

Chain	Residue
F	GLN27
F	SER28
F	ASN92
H	LYS50

---

site_id	AG3
Number of Residues	1
Details	binding site for residue EDO F 305

Chain	Residue
F	GLN100

---

site_id	AG4
Number of Residues	1
Details	binding site for residue EDO F 306

Chain	Residue
F	LYS42

---

site_id	AG5
Number of Residues	2
Details	binding site for residue EDO F 307

Chain	Residue
B	GLU143
F	EDO301

---

site_id	AG6
Number of Residues	4
Details	binding site for residue PEG F 308

Chain	Residue
E	GLY42
F	GLN38
F	THR85
F	TYR87

---

site_id	AG7
Number of Residues	2
Details	binding site for residue PEG F 309

Chain	Residue
D	PEG309
F	SER171

---

site_id	AG8
Number of Residues	3
Details	binding site for residue EDO G 301

Chain	Residue
B	SER203
G	TYR32
G	ASP97

---

site_id	AG9
Number of Residues	1
Details	binding site for residue EDO H 301

Chain	Residue
H	SER9

---

site_id	AH1
Number of Residues	3
Details	binding site for residue EDO H 302

Chain	Residue
H	ARG18
H	SER63
H	EDO304

---

site_id	AH2
Number of Residues	5
Details	binding site for residue EDO H 303

Chain	Residue
H	GLN37
H	LYS45
H	LEU47
H	PRO59
H	ASP81

---

site_id	AH3
Number of Residues	2
Details	binding site for residue EDO H 304

Chain	Residue
B	PEG313
H	EDO302

---

site_id	AH4
Number of Residues	2
Details	binding site for residue EDO I 101

Chain	Residue
A	TRP52
I	ASN15

---

site_id	AH5
Number of Residues	3
Details	binding site for residue EDO I 102

Chain	Residue
A	TYR100
C	TRP52
I	ASN7

---

site_id	AH6
Number of Residues	2
Details	binding site for residue EDO I 103

Chain	Residue
A	ASP97
I	ASN19

---

site_id	AH7
Number of Residues	3
Details	binding site for residue EDO J 101

Chain	Residue
E	TYR100
G	TRP52
J	ASN7

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
A	TYR194-HIS200
B	TYR192-HIS198

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Repeat: {"description":"38","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Repeat: {"description":"39","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Repeat: {"description":"40","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Repeat: {"description":"41","evidences":[{"source":"PubMed","id":"6204383","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---