6CJP
Candida albicans Hsp90 nucleotide binding domain in complex with radicicol
Summary for 6CJP
Entry DOI | 10.2210/pdb6cjp/pdb |
Related | 6CJI 6CJJ 6CJL |
Descriptor | Heat shock protein 90 homolog, (1aR,2Z,4E,6E,14R,15aR)-9,11-dihydroxy-6-{[(4-methoxyphenyl)methoxy]imino}-14-methyl-1a,6,7,14,15,15a-hexahydro-12H-oxireno[e][2]benzoxacyclotetradecin-12-one (3 entities in total) |
Functional Keywords | hsp90. atpase, chaperone |
Biological source | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) |
Total number of polymer chains | 2 |
Total formula weight | 53348.27 |
Authors | Nation, C.,Pizarro, J.C. (deposition date: 2018-02-26, release date: 2019-01-30, Last modification date: 2023-10-04) |
Primary citation | Whitesell, L.,Robbins, N.,Huang, D.S.,McLellan, C.A.,Shekhar-Guturja, T.,LeBlanc, E.V.,Nation, C.S.,Hui, R.,Hutchinson, A.,Collins, C.,Chatterjee, S.,Trilles, R.,Xie, J.L.,Krysan, D.J.,Lindquist, S.,Porco Jr., J.A.,Tatu, U.,Brown, L.E.,Pizarro, J.,Cowen, L.E. Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Nat Commun, 10:402-402, 2019 Cited by PubMed: 30679438DOI: 10.1038/s41467-018-08248-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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