6C7S
Structure of Rifampicin Monooxygenase with Product Bound
Summary for 6C7S
Entry DOI | 10.2210/pdb6c7s/pdb |
Related | 5KOW 5KOX |
Descriptor | Putative rifampin monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, (1E,3S,4R,5S,6R,7R,8R,9S,10S,11E,13E)-15-amino-1-{[(2S)-5,7-dihydroxy-2,4-dimethyl-8-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-1,6,9-trioxo-1,2,6,9-tetrahydronaphtho[2,1-b]furan-2-yl]oxy}-7,9-dihydroxy-3-methoxy-4,6,8,10,14-pentamethyl-15-oxopentadeca-1,11,13-trien-5-yl acetate, ... (6 entities in total) |
Functional Keywords | rifampicin, oxidoreductase |
Biological source | Nocardia farcinica (strain IFM 10152) |
Total number of polymer chains | 1 |
Total formula weight | 53692.33 |
Authors | Liu, L.-K.,Tanner, J.J. (deposition date: 2018-01-23, release date: 2018-04-18, Last modification date: 2023-10-04) |
Primary citation | Liu, L.K.,Dai, Y.,Abdelwahab, H.,Sobrado, P.,Tanner, J.J. Structural Evidence for Rifampicin Monooxygenase Inactivating Rifampicin by Cleaving Its Ansa-Bridge. Biochemistry, 57:2065-2068, 2018 Cited by PubMed: 29578336DOI: 10.1021/acs.biochem.8b00190 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report