6C7S
Structure of Rifampicin Monooxygenase with Product Bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| A | 0071949 | molecular_function | FAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | binding site for residue FAD A 501 |
| Chain | Residue |
| A | GLY8 |
| A | SER42 |
| A | ARG43 |
| A | GLN98 |
| A | CYS120 |
| A | GLU121 |
| A | VAL122 |
| A | CYS150 |
| A | ASP151 |
| A | GLY152 |
| A | THR156 |
| A | GLY10 |
| A | LEU176 |
| A | GLY275 |
| A | ASP276 |
| A | PRO283 |
| A | GLY286 |
| A | GLN287 |
| A | GLY288 |
| A | LEU289 |
| A | ASN290 |
| A | RFH502 |
| A | PRO11 |
| A | HOH630 |
| A | HOH644 |
| A | HOH662 |
| A | HOH707 |
| A | HOH744 |
| A | HOH750 |
| A | THR12 |
| A | LEU30 |
| A | GLU31 |
| A | LYS32 |
| A | GLU33 |
| A | ARG41 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | binding site for residue RFH A 502 |
| Chain | Residue |
| A | ARG43 |
| A | VAL71 |
| A | GLY72 |
| A | GLY73 |
| A | PHE74 |
| A | ALA76 |
| A | GLY77 |
| A | ALA95 |
| A | LEU176 |
| A | ARG196 |
| A | LEU200 |
| A | ARG201 |
| A | PHE202 |
| A | GLY203 |
| A | ILE215 |
| A | PHE256 |
| A | PRO283 |
| A | THR284 |
| A | GLY285 |
| A | GLY286 |
| A | LEU341 |
| A | FAD501 |
| A | HOH615 |
| A | HOH790 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 503 |
| Chain | Residue |
| A | ARG145 |
| A | TYR146 |
| A | ARG270 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | THR229 |
| A | GLU232 |
| A | ARG235 |
| A | HOH602 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 505 |
| Chain | Residue |
| A | PRO169 |
| A | THR170 |
| A | ALA259 |
| A | ARG261 |
| A | HOH684 |
| A | HOH701 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | ARG154 |
| A | SER422 |
| A | GLY423 |
| A | SER425 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27557658","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29578336","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KOW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5KOX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6C7S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27557658","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29578336","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5KOX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6C7S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29578336","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6C7S","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
