6B8B
E. coli LptB in complex with ADP and a novobiocin derivative
Summary for 6B8B
Entry DOI | 10.2210/pdb6b8b/pdb |
Related | 6B89 |
Descriptor | Lipopolysaccharide export system ATP-binding protein LptB, MAGNESIUM ION, (3s,5s,7s)-N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-ben zopyran-3-yl}tricyclo[3.3.1.1~3,7~]decane-1-carboxamide, ... (5 entities in total) |
Functional Keywords | lptb, abc transporter, lps transport, lipid transport, lipid transport-activator complex, lipid transport/activator |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 28978.90 |
Authors | Mandler, M.D.,Owens, T.W.,Lazarus, M.B.,May, J.M.,Kahne, D.K. (deposition date: 2017-10-06, release date: 2017-12-06, Last modification date: 2023-10-04) |
Primary citation | May, J.M.,Owens, T.W.,Mandler, M.D.,Simpson, B.W.,Lazarus, M.B.,Sherman, D.J.,Davis, R.M.,Okuda, S.,Massefski, W.,Ruiz, N.,Kahne, D. The Antibiotic Novobiocin Binds and Activates the ATPase That Powers Lipopolysaccharide Transport. J. Am. Chem. Soc., 139:17221-17224, 2017 Cited by PubMed: 29135241DOI: 10.1021/jacs.7b07736 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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