Crystal Structure of HSP104 from Chaetomium thermophilum

Summary for 5ZUI

DescriptorHeat Shock Protein 104, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION, ... (4 entities in total)
Functional Keywordsprotein disaggregase, atpase, two-ring aaa protein, helical filament, chaperone
Biological sourceChaetomium thermophilum
Total number of polymer chains1
Total molecular weight86486.85
Hanazono, Y.,Inoue, Y.,Noguchi, K.,Yohda, M.,Shinohara, K.,Takeda, K.,Miki, K. (deposition date: 2018-05-07, release date: 2019-06-19)
Primary citation
Inoue, Y.,Hanazono, Y.,Noi, K.,Kawamoto, A.,Kimazuka, M.,Harada, R.,Takeda, K.,Iwamasa, N.,Noguchi, K.,Shigeta, Y.,Namba, K.,Ogura, T.,Miki, K.,Shinohara, K.,Yohda, M.
Transient splitting of the Hsp104 hexameric ring revealed by near atomic analysis and direct visual observation
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2659 0.3% 2.8% 3.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution