5ZKP

Crystal structure of the human platelet-activating factor receptor in complex with SR 27417

5ZKP の概要

• エントリーDOI: 10.2210/pdb5zkp/pdb
• 分子名称: Platelet-activating factor receptor,Flavodoxin,Platelet-activating factor receptor, N1,N1-dimethyl-N2-[(pyridin-3-yl)methyl]-N2-{4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl}ethane-1,2-diamine, FLAVIN MONONUCLEOTIDE (3 entities in total)
• 機能のキーワード: g protein-coupled receptor, platelet-activating factor receptor, complex, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 53351.53

構造登録者

Cao, C.,Zhao, Q.,Zhang, X.C.,Wu, B. (登録日: 2018-03-25, 公開日: 2018-06-20, 最終更新日: 2023-11-22)

• 主引用文献: Cao, C.,Tan, Q.,Xu, C.,He, L.,Yang, L.,Zhou, Y.,Zhou, Y.,Qiao, A.,Lu, M.,Yi, C.,Han, G.W.,Wang, X.,Li, X.,Yang, H.,Rao, Z.,Jiang, H.,Zhao, Y.,Liu, J.,Stevens, R.C.,Zhao, Q.,Zhang, X.C.,Wu, B.; Structural basis for signal recognition and transduction by platelet-activating-factor receptor.; Nat. Struct. Mol. Biol., 25:488-495, 2018; PubMed: 29808000; DOI: 10.1038/s41594-018-0068-y

実験手法

X-RAY DIFFRACTION (2.81 Å)