5ZKJ
Human EXOG-H140A in complex with RNA/DNA hybrid duplex
Summary for 5ZKJ
Entry DOI | 10.2210/pdb5zkj/pdb |
Descriptor | Nuclease EXOG, mitochondrial, RNA (5'-R(P*CP*GP*GP*GP*AP*UP*GP*UP*CP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*GP*AP*CP*AP*TP*CP*CP*CP*G)-3'), ... (6 entities in total) |
Functional Keywords | enzyme-substrate complex, mitochondrial exonuclease, hydrolase-rna-dna complex, hydrolase/rna/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 93498.04 |
Authors | Wu, C.C.,Lin, J.L.J.,Yuan, H.S. (deposition date: 2018-03-24, release date: 2019-04-03, Last modification date: 2023-11-22) |
Primary citation | Wu, C.C.,Lin, J.L.J.,Yang-Yen, H.F.,Yuan, H.S. A unique exonuclease ExoG cleaves between RNA and DNA in mitochondrial DNA replication. Nucleic Acids Res., 47:5405-5419, 2019 Cited by PubMed: 30949702DOI: 10.1093/nar/gkz241 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.798 Å) |
Structure validation
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