5ZHX
Crystal structure of SmgGDS-558 and farnesylated RhoA complex
Summary for 5ZHX
Entry DOI | 10.2210/pdb5zhx/pdb |
Descriptor | Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA, FARNESYL (3 entities in total) |
Functional Keywords | armadillo gef chaperone, oncoprotein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 303175.37 |
Authors | Shimizu, H.,Toma-Fukai, S.,Shimizu, T. (deposition date: 2018-03-13, release date: 2018-09-05, Last modification date: 2018-10-03) |
Primary citation | Shimizu, H.,Toma-Fukai, S.,Kontani, K.,Katada, T.,Shimizu, T. GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism. Proc. Natl. Acad. Sci. U.S.A., 115:9563-9568, 2018 Cited by PubMed: 30190425DOI: 10.1073/pnas.1804740115 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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