5ZHX

Crystal structure of SmgGDS-558 and farnesylated RhoA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005085	molecular_function	guanyl-nucleotide exchange factor activity
A	0043547	biological_process	positive regulation of GTPase activity
B	0005085	molecular_function	guanyl-nucleotide exchange factor activity
B	0043547	biological_process	positive regulation of GTPase activity
C	0005085	molecular_function	guanyl-nucleotide exchange factor activity
C	0043547	biological_process	positive regulation of GTPase activity
D	0005085	molecular_function	guanyl-nucleotide exchange factor activity
D	0043547	biological_process	positive regulation of GTPase activity
e	0000166	molecular_function	nucleotide binding
e	0000281	biological_process	mitotic cytokinesis
e	0002363	biological_process	alpha-beta T cell lineage commitment
e	0003189	biological_process	aortic valve formation
e	0003924	molecular_function	GTPase activity
e	0003925	molecular_function	G protein activity
e	0005515	molecular_function	protein binding
e	0005525	molecular_function	GTP binding
e	0005634	cellular_component	nucleus
e	0005737	cellular_component	cytoplasm
e	0005768	cellular_component	endosome
e	0005789	cellular_component	endoplasmic reticulum membrane
e	0005829	cellular_component	cytosol
e	0005856	cellular_component	cytoskeleton
e	0005886	cellular_component	plasma membrane
e	0005925	cellular_component	focal adhesion
e	0005938	cellular_component	cell cortex
e	0007264	biological_process	small GTPase-mediated signal transduction
e	0007266	biological_process	Rho protein signal transduction
e	0009898	cellular_component	cytoplasmic side of plasma membrane
e	0010812	biological_process	negative regulation of cell-substrate adhesion
e	0016477	biological_process	cell migration
e	0016787	molecular_function	hydrolase activity
e	0017022	molecular_function	myosin binding
e	0019901	molecular_function	protein kinase binding
e	0021762	biological_process	substantia nigra development
e	0030027	cellular_component	lamellipodium
e	0030036	biological_process	actin cytoskeleton organization
e	0030054	cellular_component	cell junction
e	0030334	biological_process	regulation of cell migration
e	0030335	biological_process	positive regulation of cell migration
e	0030425	cellular_component	dendrite
e	0030496	cellular_component	midbody
e	0030667	cellular_component	secretory granule membrane
e	0031122	biological_process	cytoplasmic microtubule organization
e	0031982	cellular_component	vesicle
e	0032154	cellular_component	cleavage furrow
e	0032467	biological_process	positive regulation of cytokinesis
e	0032587	cellular_component	ruffle membrane
e	0032956	biological_process	regulation of actin cytoskeleton organization
e	0033688	biological_process	regulation of osteoblast proliferation
e	0034329	biological_process	cell junction assembly
e	0034446	biological_process	substrate adhesion-dependent cell spreading
e	0035385	biological_process	Roundabout signaling pathway
e	0036089	biological_process	cleavage furrow formation
e	0038027	biological_process	apolipoprotein A-I-mediated signaling pathway
e	0042476	biological_process	odontogenesis
e	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
e	0043149	biological_process	stress fiber assembly
e	0043197	cellular_component	dendritic spine
e	0043296	cellular_component	apical junction complex
e	0043297	biological_process	apical junction assembly
e	0043366	biological_process	beta selection
e	0043542	biological_process	endothelial cell migration
e	0043931	biological_process	ossification involved in bone maturation
e	0044319	biological_process	wound healing, spreading of cells
e	0045198	biological_process	establishment of epithelial cell apical/basal polarity
e	0045666	biological_process	positive regulation of neuron differentiation
e	0045792	biological_process	negative regulation of cell size
e	0046638	biological_process	positive regulation of alpha-beta T cell differentiation
e	0050919	biological_process	negative chemotaxis
e	0051301	biological_process	cell division
e	0051496	biological_process	positive regulation of stress fiber assembly
e	0051893	biological_process	regulation of focal adhesion assembly
e	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
e	0060193	biological_process	positive regulation of lipase activity
e	0061430	biological_process	bone trabecula morphogenesis
e	0070062	cellular_component	extracellular exosome
e	0070507	biological_process	regulation of microtubule cytoskeleton organization
e	0071222	biological_process	cellular response to lipopolysaccharide
e	0071345	biological_process	cellular response to cytokine stimulus
e	0071526	biological_process	semaphorin-plexin signaling pathway
e	0071902	biological_process	positive regulation of protein serine/threonine kinase activity
e	0071944	cellular_component	cell periphery
e	0090051	biological_process	negative regulation of cell migration involved in sprouting angiogenesis
e	0090307	biological_process	mitotic spindle assembly
e	0090324	biological_process	negative regulation of oxidative phosphorylation
e	0097498	biological_process	endothelial tube lumen extension
e	0098794	cellular_component	postsynapse
e	0098978	cellular_component	glutamatergic synapse
e	0099159	biological_process	regulation of modification of postsynaptic structure
e	0101003	cellular_component	ficolin-1-rich granule membrane
e	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
e	1902766	biological_process	skeletal muscle satellite cell migration
e	1903427	biological_process	negative regulation of reactive oxygen species biosynthetic process
e	1903673	biological_process	mitotic cleavage furrow formation
e	1904996	biological_process	positive regulation of leukocyte adhesion to vascular endothelial cell
e	1905274	biological_process	regulation of modification of postsynaptic actin cytoskeleton
e	1990869	biological_process	cellular response to chemokine
e	2000406	biological_process	positive regulation of T cell migration
f	0000166	molecular_function	nucleotide binding
f	0000281	biological_process	mitotic cytokinesis
f	0002363	biological_process	alpha-beta T cell lineage commitment
f	0003189	biological_process	aortic valve formation
f	0003924	molecular_function	GTPase activity
f	0003925	molecular_function	G protein activity
f	0005515	molecular_function	protein binding
f	0005525	molecular_function	GTP binding
f	0005634	cellular_component	nucleus
f	0005737	cellular_component	cytoplasm
f	0005768	cellular_component	endosome
f	0005789	cellular_component	endoplasmic reticulum membrane
f	0005829	cellular_component	cytosol
f	0005856	cellular_component	cytoskeleton
f	0005886	cellular_component	plasma membrane
f	0005925	cellular_component	focal adhesion
f	0005938	cellular_component	cell cortex
f	0007264	biological_process	small GTPase-mediated signal transduction
f	0007266	biological_process	Rho protein signal transduction
f	0009898	cellular_component	cytoplasmic side of plasma membrane
f	0010812	biological_process	negative regulation of cell-substrate adhesion
f	0016477	biological_process	cell migration
f	0016787	molecular_function	hydrolase activity
f	0017022	molecular_function	myosin binding
f	0019901	molecular_function	protein kinase binding
f	0021762	biological_process	substantia nigra development
f	0030027	cellular_component	lamellipodium
f	0030036	biological_process	actin cytoskeleton organization
f	0030054	cellular_component	cell junction
f	0030334	biological_process	regulation of cell migration
f	0030335	biological_process	positive regulation of cell migration
f	0030425	cellular_component	dendrite
f	0030496	cellular_component	midbody
f	0030667	cellular_component	secretory granule membrane
f	0031122	biological_process	cytoplasmic microtubule organization
f	0031982	cellular_component	vesicle
f	0032154	cellular_component	cleavage furrow
f	0032467	biological_process	positive regulation of cytokinesis
f	0032587	cellular_component	ruffle membrane
f	0032956	biological_process	regulation of actin cytoskeleton organization
f	0033688	biological_process	regulation of osteoblast proliferation
f	0034329	biological_process	cell junction assembly
f	0034446	biological_process	substrate adhesion-dependent cell spreading
f	0035385	biological_process	Roundabout signaling pathway
f	0036089	biological_process	cleavage furrow formation
f	0038027	biological_process	apolipoprotein A-I-mediated signaling pathway
f	0042476	biological_process	odontogenesis
f	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
f	0043149	biological_process	stress fiber assembly
f	0043197	cellular_component	dendritic spine
f	0043296	cellular_component	apical junction complex
f	0043297	biological_process	apical junction assembly
f	0043366	biological_process	beta selection
f	0043542	biological_process	endothelial cell migration
f	0043931	biological_process	ossification involved in bone maturation
f	0044319	biological_process	wound healing, spreading of cells
f	0045198	biological_process	establishment of epithelial cell apical/basal polarity
f	0045666	biological_process	positive regulation of neuron differentiation
f	0045792	biological_process	negative regulation of cell size
f	0046638	biological_process	positive regulation of alpha-beta T cell differentiation
f	0050919	biological_process	negative chemotaxis
f	0051301	biological_process	cell division
f	0051496	biological_process	positive regulation of stress fiber assembly
f	0051893	biological_process	regulation of focal adhesion assembly
f	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
f	0060193	biological_process	positive regulation of lipase activity
f	0061430	biological_process	bone trabecula morphogenesis
f	0070062	cellular_component	extracellular exosome
f	0070507	biological_process	regulation of microtubule cytoskeleton organization
f	0071222	biological_process	cellular response to lipopolysaccharide
f	0071345	biological_process	cellular response to cytokine stimulus
f	0071526	biological_process	semaphorin-plexin signaling pathway
f	0071902	biological_process	positive regulation of protein serine/threonine kinase activity
f	0071944	cellular_component	cell periphery
f	0090051	biological_process	negative regulation of cell migration involved in sprouting angiogenesis
f	0090307	biological_process	mitotic spindle assembly
f	0090324	biological_process	negative regulation of oxidative phosphorylation
f	0097498	biological_process	endothelial tube lumen extension
f	0098794	cellular_component	postsynapse
f	0098978	cellular_component	glutamatergic synapse
f	0099159	biological_process	regulation of modification of postsynaptic structure
f	0101003	cellular_component	ficolin-1-rich granule membrane
f	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
f	1902766	biological_process	skeletal muscle satellite cell migration
f	1903427	biological_process	negative regulation of reactive oxygen species biosynthetic process
f	1903673	biological_process	mitotic cleavage furrow formation
f	1904996	biological_process	positive regulation of leukocyte adhesion to vascular endothelial cell
f	1905274	biological_process	regulation of modification of postsynaptic actin cytoskeleton
f	1990869	biological_process	cellular response to chemokine
f	2000406	biological_process	positive regulation of T cell migration
g	0000166	molecular_function	nucleotide binding
g	0000281	biological_process	mitotic cytokinesis
g	0002363	biological_process	alpha-beta T cell lineage commitment
g	0003189	biological_process	aortic valve formation
g	0003924	molecular_function	GTPase activity
g	0003925	molecular_function	G protein activity
g	0005515	molecular_function	protein binding
g	0005525	molecular_function	GTP binding
g	0005634	cellular_component	nucleus
g	0005737	cellular_component	cytoplasm
g	0005768	cellular_component	endosome
g	0005789	cellular_component	endoplasmic reticulum membrane
g	0005829	cellular_component	cytosol
g	0005856	cellular_component	cytoskeleton
g	0005886	cellular_component	plasma membrane
g	0005925	cellular_component	focal adhesion
g	0005938	cellular_component	cell cortex
g	0007264	biological_process	small GTPase-mediated signal transduction
g	0007266	biological_process	Rho protein signal transduction
g	0009898	cellular_component	cytoplasmic side of plasma membrane
g	0010812	biological_process	negative regulation of cell-substrate adhesion
g	0016477	biological_process	cell migration
g	0016787	molecular_function	hydrolase activity
g	0017022	molecular_function	myosin binding
g	0019901	molecular_function	protein kinase binding
g	0021762	biological_process	substantia nigra development
g	0030027	cellular_component	lamellipodium
g	0030036	biological_process	actin cytoskeleton organization
g	0030054	cellular_component	cell junction
g	0030334	biological_process	regulation of cell migration
g	0030335	biological_process	positive regulation of cell migration
g	0030425	cellular_component	dendrite
g	0030496	cellular_component	midbody
g	0030667	cellular_component	secretory granule membrane
g	0031122	biological_process	cytoplasmic microtubule organization
g	0031982	cellular_component	vesicle
g	0032154	cellular_component	cleavage furrow
g	0032467	biological_process	positive regulation of cytokinesis
g	0032587	cellular_component	ruffle membrane
g	0032956	biological_process	regulation of actin cytoskeleton organization
g	0033688	biological_process	regulation of osteoblast proliferation
g	0034329	biological_process	cell junction assembly
g	0034446	biological_process	substrate adhesion-dependent cell spreading
g	0035385	biological_process	Roundabout signaling pathway
g	0036089	biological_process	cleavage furrow formation
g	0038027	biological_process	apolipoprotein A-I-mediated signaling pathway
g	0042476	biological_process	odontogenesis
g	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
g	0043149	biological_process	stress fiber assembly
g	0043197	cellular_component	dendritic spine
g	0043296	cellular_component	apical junction complex
g	0043297	biological_process	apical junction assembly
g	0043366	biological_process	beta selection
g	0043542	biological_process	endothelial cell migration
g	0043931	biological_process	ossification involved in bone maturation
g	0044319	biological_process	wound healing, spreading of cells
g	0045198	biological_process	establishment of epithelial cell apical/basal polarity
g	0045666	biological_process	positive regulation of neuron differentiation
g	0045792	biological_process	negative regulation of cell size
g	0046638	biological_process	positive regulation of alpha-beta T cell differentiation
g	0050919	biological_process	negative chemotaxis
g	0051301	biological_process	cell division
g	0051496	biological_process	positive regulation of stress fiber assembly
g	0051893	biological_process	regulation of focal adhesion assembly
g	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
g	0060193	biological_process	positive regulation of lipase activity
g	0061430	biological_process	bone trabecula morphogenesis
g	0070062	cellular_component	extracellular exosome
g	0070507	biological_process	regulation of microtubule cytoskeleton organization
g	0071222	biological_process	cellular response to lipopolysaccharide
g	0071345	biological_process	cellular response to cytokine stimulus
g	0071526	biological_process	semaphorin-plexin signaling pathway
g	0071902	biological_process	positive regulation of protein serine/threonine kinase activity
g	0071944	cellular_component	cell periphery
g	0090051	biological_process	negative regulation of cell migration involved in sprouting angiogenesis
g	0090307	biological_process	mitotic spindle assembly
g	0090324	biological_process	negative regulation of oxidative phosphorylation
g	0097498	biological_process	endothelial tube lumen extension
g	0098794	cellular_component	postsynapse
g	0098978	cellular_component	glutamatergic synapse
g	0099159	biological_process	regulation of modification of postsynaptic structure
g	0101003	cellular_component	ficolin-1-rich granule membrane
g	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
g	1902766	biological_process	skeletal muscle satellite cell migration
g	1903427	biological_process	negative regulation of reactive oxygen species biosynthetic process
g	1903673	biological_process	mitotic cleavage furrow formation
g	1904996	biological_process	positive regulation of leukocyte adhesion to vascular endothelial cell
g	1905274	biological_process	regulation of modification of postsynaptic actin cytoskeleton
g	1990869	biological_process	cellular response to chemokine
g	2000406	biological_process	positive regulation of T cell migration
h	0000166	molecular_function	nucleotide binding
h	0000281	biological_process	mitotic cytokinesis
h	0002363	biological_process	alpha-beta T cell lineage commitment
h	0003189	biological_process	aortic valve formation
h	0003924	molecular_function	GTPase activity
h	0003925	molecular_function	G protein activity
h	0005515	molecular_function	protein binding
h	0005525	molecular_function	GTP binding
h	0005634	cellular_component	nucleus
h	0005737	cellular_component	cytoplasm
h	0005768	cellular_component	endosome
h	0005789	cellular_component	endoplasmic reticulum membrane
h	0005829	cellular_component	cytosol
h	0005856	cellular_component	cytoskeleton
h	0005886	cellular_component	plasma membrane
h	0005925	cellular_component	focal adhesion
h	0005938	cellular_component	cell cortex
h	0007264	biological_process	small GTPase-mediated signal transduction
h	0007266	biological_process	Rho protein signal transduction
h	0009898	cellular_component	cytoplasmic side of plasma membrane
h	0010812	biological_process	negative regulation of cell-substrate adhesion
h	0016477	biological_process	cell migration
h	0016787	molecular_function	hydrolase activity
h	0017022	molecular_function	myosin binding
h	0019901	molecular_function	protein kinase binding
h	0021762	biological_process	substantia nigra development
h	0030027	cellular_component	lamellipodium
h	0030036	biological_process	actin cytoskeleton organization
h	0030054	cellular_component	cell junction
h	0030334	biological_process	regulation of cell migration
h	0030335	biological_process	positive regulation of cell migration
h	0030425	cellular_component	dendrite
h	0030496	cellular_component	midbody
h	0030667	cellular_component	secretory granule membrane
h	0031122	biological_process	cytoplasmic microtubule organization
h	0031982	cellular_component	vesicle
h	0032154	cellular_component	cleavage furrow
h	0032467	biological_process	positive regulation of cytokinesis
h	0032587	cellular_component	ruffle membrane
h	0032956	biological_process	regulation of actin cytoskeleton organization
h	0033688	biological_process	regulation of osteoblast proliferation
h	0034329	biological_process	cell junction assembly
h	0034446	biological_process	substrate adhesion-dependent cell spreading
h	0035385	biological_process	Roundabout signaling pathway
h	0036089	biological_process	cleavage furrow formation
h	0038027	biological_process	apolipoprotein A-I-mediated signaling pathway
h	0042476	biological_process	odontogenesis
h	0043123	biological_process	positive regulation of canonical NF-kappaB signal transduction
h	0043149	biological_process	stress fiber assembly
h	0043197	cellular_component	dendritic spine
h	0043296	cellular_component	apical junction complex
h	0043297	biological_process	apical junction assembly
h	0043366	biological_process	beta selection
h	0043542	biological_process	endothelial cell migration
h	0043931	biological_process	ossification involved in bone maturation
h	0044319	biological_process	wound healing, spreading of cells
h	0045198	biological_process	establishment of epithelial cell apical/basal polarity
h	0045666	biological_process	positive regulation of neuron differentiation
h	0045792	biological_process	negative regulation of cell size
h	0046638	biological_process	positive regulation of alpha-beta T cell differentiation
h	0050919	biological_process	negative chemotaxis
h	0051301	biological_process	cell division
h	0051496	biological_process	positive regulation of stress fiber assembly
h	0051893	biological_process	regulation of focal adhesion assembly
h	0060071	biological_process	Wnt signaling pathway, planar cell polarity pathway
h	0060193	biological_process	positive regulation of lipase activity
h	0061430	biological_process	bone trabecula morphogenesis
h	0070062	cellular_component	extracellular exosome
h	0070507	biological_process	regulation of microtubule cytoskeleton organization
h	0071222	biological_process	cellular response to lipopolysaccharide
h	0071345	biological_process	cellular response to cytokine stimulus
h	0071526	biological_process	semaphorin-plexin signaling pathway
h	0071902	biological_process	positive regulation of protein serine/threonine kinase activity
h	0071944	cellular_component	cell periphery
h	0090051	biological_process	negative regulation of cell migration involved in sprouting angiogenesis
h	0090307	biological_process	mitotic spindle assembly
h	0090324	biological_process	negative regulation of oxidative phosphorylation
h	0097498	biological_process	endothelial tube lumen extension
h	0098794	cellular_component	postsynapse
h	0098978	cellular_component	glutamatergic synapse
h	0099159	biological_process	regulation of modification of postsynaptic structure
h	0101003	cellular_component	ficolin-1-rich granule membrane
h	1901224	biological_process	positive regulation of non-canonical NF-kappaB signal transduction
h	1902766	biological_process	skeletal muscle satellite cell migration
h	1903427	biological_process	negative regulation of reactive oxygen species biosynthetic process
h	1903673	biological_process	mitotic cleavage furrow formation
h	1904996	biological_process	positive regulation of leukocyte adhesion to vascular endothelial cell
h	1905274	biological_process	regulation of modification of postsynaptic actin cytoskeleton
h	1990869	biological_process	cellular response to chemokine
h	2000406	biological_process	positive regulation of T cell migration

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for Di-peptide FAR e 201 and CYS e 190

Chain	Residue
A	CYS117
A	TYR118
A	GLN124
A	LEU127
A	LEU136
A	MET152
e	LEU191

---

site_id	AC2
Number of Residues	9
Details	binding site for Di-peptide FAR f 201 and CYS f 190

Chain	Residue
B	LEU136
B	LEU139
B	MET152
B	CYS153
B	VAL155
f	GLY189
f	LEU191
B	TYR118
B	GLN124

---

site_id	AC3
Number of Residues	10
Details	binding site for Di-peptide FAR g 201 and CYS g 190

Chain	Residue
C	GLN124
C	LEU136
C	LEU139
C	LEU149
C	MET152
C	CYS153
C	VAL155
C	ASN159
g	GLY189
g	LEU191

---

site_id	AC4
Number of Residues	6
Details	binding site for Di-peptide FAR h 201 and CYS h 190

Chain	Residue
D	CYS117
D	TYR118
D	GLN124
D	MET152
D	ASN159
h	LEU191

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	172
Details	Repeat: {"description":"ARM 3","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	160
Details	Repeat: {"description":"ARM 4","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	160
Details	Repeat: {"description":"ARM 5","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	64
Details	Region: {"description":"Interacts with polybasic regions in GTPases","evidences":[{"source":"PubMed","id":"21242305","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28630045","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	196
Details	Region: {"description":"Critical for catalytic activity","evidences":[{"source":"PubMed","id":"21242305","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28630045","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	26
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10748207","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12777804","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P62820","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	Modified residue: {"description":"(Microbial infection) ADP-ribosylasparagine; by botulinum toxin","evidences":[{"source":"PubMed","id":"1328215","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	Modified residue: {"description":"Cysteine methyl ester","evidences":[{"source":"UniProtKB","id":"P61585","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	4
Details	Lipidation: {"description":"S-geranylgeranyl cysteine","evidences":[{"source":"UniProtKB","id":"P61585","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"23871831","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	2
Details	Site: {"description":"(Microbial infection) Cleavage; by yopT","evidences":[{"source":"PubMed","id":"12062101","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12538863","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by PKG/PRKG1","evidences":[{"source":"PubMed","id":"11162591","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	6
Details	Lipidation: {"description":"(Microbial infection) N6-stearoyl lysine","evidences":[{"source":"PubMed","id":"30061757","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---