5ZEC

Crystal structure of Kluyveromyces polyspora ADH (KpADH) mutant (Q136N/F161V/S196G/E214G/S237C)

Summary for 5ZEC

Entry DOI	10.2210/pdb5zec/pdb
Descriptor	Uncharacterized protein ADH, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 1,2-ETHANEDIOL, ... (8 entities in total)
Functional Keywords	alcohol dehydrogenase(kpadh), nadph, isomerase
Biological source	Vanderwaltozyma polyspora DSM 70294 (Kluyveromyces polysporus)
Total number of polymer chains	2
Total formula weight	79765.70
Authors	Wang, Y.,ZHou, J.Y.,Hou, X.D.,Xu, G.C.,Rao, Y.J.,Wu, L.,Zhou, J.H.,Ni, Y. (deposition date: 2018-02-27, release date: 2019-01-02, Last modification date: 2023-11-22)
Primary citation	Zhou, J.Y.,Wang, Y.,Xu, G.C.,Wu, L.,Han, R.Z.,Schwaneberg, U.,Rao, Y.J.,Zhao, Y.L.,Zhou, J.H.,Ni, Y. Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones. J. Am. Chem. Soc., 140:12645-12654, 2018 Cited by PubMed: 30247889 DOI: 10.1021/jacs.8b08640 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.779 Å)

Structure validation