5ZBH
The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885
Summary for 5ZBH
Entry DOI | 10.2210/pdb5zbh/pdb |
Descriptor | Neuropeptide Y receptor type 1,T4 Lysozyme,Neuropeptide Y receptor type 1, dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate (2 entities in total) |
Functional Keywords | g protein-coupled receptor neuropeptide y y1 receptor inhibitor complex structure, signaling protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P25929 |
Total number of polymer chains | 1 |
Total formula weight | 61255.73 |
Authors | |
Primary citation | Yang, Z.,Han, S.,Keller, M.,Kaiser, A.,Bender, B.J.,Bosse, M.,Burkert, K.,Kogler, L.M.,Wifling, D.,Bernhardt, G.,Plank, N.,Littmann, T.,Schmidt, P.,Yi, C.,Li, B.,Ye, S.,Zhang, R.,Xu, B.,Larhammar, D.,Stevens, R.C.,Huster, D.,Meiler, J.,Zhao, Q.,Beck-Sickinger, A.G.,Buschauer, A.,Wu, B. Structural basis of ligand binding modes at the neuropeptide Y Y1receptor Nature, 556:520-524, 2018 Cited by PubMed: 29670288DOI: 10.1038/s41586-018-0046-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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