5ZBH
The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Neuropeptide Y receptor type 1,T4 Lysozyme,Neuropeptide Y receptor type 1 | polymer | 527 | 60665.0 | 1 | UniProt (P25929) UniProt (D9IEF7) Pfam (PF00001) Pfam (PF00959) UniProt (by SIFTS) (P00720) In PDB | Homo sapiens (Human) | NPY1-R,Lysis protein,Lysozyme,Muramidase,NPY1-R |
2 | A | dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate | non-polymer | 590.7 | 1 | Chemie (9AF) |
Sequence modifications
A: 2 - 241 (UniProt: P25929)
A: 1001 - 1160 (UniProt: D9IEF7)
A: 250 - 358 (UniProt: P25929)
PDB | External Database | Details |
---|---|---|
Asp -8 | - | expression tag |
Tyr -7 | - | expression tag |
Lys -6 | - | expression tag |
Asp -5 | - | expression tag |
Asp -4 | - | expression tag |
Asp -3 | - | expression tag |
Asp -2 | - | expression tag |
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Pro 1 | - | expression tag |
Trp 129 | Phe 129 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Thr 1053 | Cys 54 | engineered mutation |
Ala 1096 | Cys 97 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Glu 359 | - | expression tag |
Phe 360 | - | expression tag |
Leu 361 | - | expression tag |
Glu 362 | - | expression tag |
Val 363 | - | expression tag |
Leu 364 | - | expression tag |
Phe 365 | - | expression tag |
Gln 366 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 60665.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 590.7 | |
All* | Total formula weight | 61255.7 |