5Z98
Crystal Structure of the Primate APOBEC3H Dimer mediated by RNA Duplex
Summary for 5Z98
Entry DOI | 10.2210/pdb5z98/pdb |
Descriptor | Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like protein 3H, RNA (5'-R(P*CP*UP*GP*CP*CP*GP*GP*GP*UP*A)-3'), RNA (5'-R(*AP*UP*AP*CP*CP*CP*GP*GP*CP*A)-3'), ... (5 entities in total) |
Functional Keywords | apobec3, apobec3h, cytidine deaminase, deaminase, anti-hiv, vif, dsrna, cancer, hiv-1, siv, chimpanzee, dimerization, pan troglodytes, antiviral protein-rna complex, antiviral protein/rna |
Biological source | Pan troglodytes (Chimpanzee) More |
Total number of polymer chains | 4 |
Total formula weight | 50308.35 |
Authors | Matsuoka, T.,Nagae, T.,Ode, H.,Watanabe, N.,Iwatani, Y. (deposition date: 2018-02-02, release date: 2018-08-15, Last modification date: 2023-11-22) |
Primary citation | Matsuoka, T.,Nagae, T.,Ode, H.,Awazu, H.,Kurosawa, T.,Hamano, A.,Matsuoka, K.,Hachiya, A.,Imahashi, M.,Yokomaku, Y.,Watanabe, N.,Iwatani, Y. Structural basis of chimpanzee APOBEC3H dimerization stabilized by double-stranded RNA. Nucleic Acids Res., 46:10368-10379, 2018 Cited by PubMed: 30060196DOI: 10.1093/nar/gky676 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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