Crystal structure of paFAN1 bound to 2nt 5'flap DNA with gap with Manganese

Summary for 5Z6W

DescriptorFanconi-associated nuclease 1 homolog, DNA (5'-D(P*GP*TP*TP*GP*GP*GP*AP*TP*TP*G)-3'), DNA (5'-D(P*AP*TP*TP*CP*AP*A)-3'), ... (6 entities in total)
Functional Keywordsnuclease, hydrolase-dna complex, hydrolase/dna
Biological sourcePseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Total number of polymer chains4
Total molecular weight81368.51
Jin, H.,Cho, Y. (deposition date: 2018-01-25, release date: 2018-03-14, Last modification date: 2018-05-09)
Primary citation
Jin, H.,Roy, U.,Lee, G.,Scharer, O.D.,Cho, Y.
Structural mechanism of DNA interstrand cross-link unhooking by the bacterial FAN1 nuclease.
J. Biol. Chem., 293:6482-6496, 2018
PubMed: 29514982 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.RA118.002171
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23870.6%8.5%0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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