5YVT
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+) and NADH
Summary for 5YVT
Entry DOI | 10.2210/pdb5yvt/pdb |
Descriptor | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | nadh, inhibition, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Cellular location | Mitochondrion: P50213 P51553 |
Total number of polymer chains | 2 |
Total formula weight | 76904.89 |
Authors | |
Primary citation | Liu, Y.,Hu, L.,Ma, T.,Yang, J.,Ding, J. Insights into the inhibitory mechanisms of NADH on the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase. Sci Rep, 8:3146-3146, 2018 Cited by PubMed: 29453450DOI: 10.1038/s41598-018-21584-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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