5YVT
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+) and NADH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial | polymer | 339 | 36682.2 | 1 | UniProt (P50213) Pfam (PF00180) | Homo sapiens (Human) | Isocitric dehydrogenase subunit alpha,NAD(+)-specific ICDH subunit alpha |
| 2 | B (B) | Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial | polymer | 354 | 38867.5 | 1 | UniProt (P51553) Pfam (PF00180) | Homo sapiens (Human) | NAD-IDH gamma subunit, Isocitric dehydrogenase subunit gamma,NAD(+)-specific ICDH subunit gamma |
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E (A, B) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 2 | Chemie (NAI) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75549.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1355.2 | |
| All* | Total formula weight | 76904.9 |
