5YV9
Structure of CaMKK2 in complex with CKI-009
Summary for 5YV9
Entry DOI | 10.2210/pdb5yv9/pdb |
Descriptor | Calcium/calmodulin-dependent protein kinase kinase 2, 5-chloro-2-methoxy-4[(1Z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid, GLYCEROL, ... (5 entities in total) |
Functional Keywords | atp-binding, kinase, serine/threonine-protein kinase, transferase, protein-inhibitor complex |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 34293.05 |
Authors | Niwa, H.,Handa, N.,Yokoyama, S. (deposition date: 2017-11-24, release date: 2018-12-05, Last modification date: 2024-10-09) |
Primary citation | Takaya, D.,Niwa, H.,Mikuni, J.,Nakamura, K.,Handa, N.,Tanaka, A.,Yokoyama, S.,Honma, T. Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method. J.Mol.Graph.Model., 99:107599-107599, 2020 Cited by PubMed: 32348940DOI: 10.1016/j.jmgm.2020.107599 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.53 Å) |
Structure validation
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