5YV9
Structure of CaMKK2 in complex with CKI-009
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Calcium/calmodulin-dependent protein kinase kinase 2 | polymer | 298 | 33711.6 | 1 | UniProt (Q96RR4) Pfam (PF00069) | Homo sapiens (Human) | CaMKK 2,Calcium/calmodulin-dependent protein kinase kinase beta,CaMKK beta |
| 2 | B (A) | 5-chloro-2-methoxy-4[(1Z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid | non-polymer | 361.8 | 1 | Chemie (91O) | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | F (A) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence modifications
A: 158 - 448 (UniProt: Q96RR4)
| PDB | External Database | Details |
|---|---|---|
| Gly 151 | - | expression tag |
| Ser 152 | - | expression tag |
| Ser 153 | - | expression tag |
| Gly 154 | - | expression tag |
| Ser 155 | - | expression tag |
| Ser 156 | - | expression tag |
| Gly 157 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33711.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 581.4 | |
| All* | Total formula weight | 34293.1 |
