5YTY

Crystal structure of echinomycin-d(ACGACGT/ACGTCGT) complex

Summary for 5YTY

• Entry DOI: 10.2210/pdb5yty/pdb
• Related PRD ID: PRD_000491
• Descriptor: DNA (5'-D(P*AP*CP*GP*AP*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*TP*CP*GP*T)-3'), echinomycin, ... (7 entities in total)
• Functional Keywords: dna intercalator, echinomycin-dna complex, watson-crick, heptamer duplex, antibiotic-dna complex, antibiotic/dna
• Biological source: Streptomyces echinatus; More
• Total number of polymer chains: 4
• Total formula weight: 6654.02

Authors

Hou, M.H.,Wu, P.C.,Kao, Y.F. (deposition date: 2017-11-20, release date: 2018-05-23, Last modification date: 2023-11-22)

• Primary citation: Wu, P.C.,Tzeng, S.L.,Chang, C.K.,Kao, Y.F.,Waring, M.J.,Hou, M.H.; Cooperative recognition of T:T mismatch by echinomycin causes structural distortions in DNA duplex; Nucleic Acids Res., 46:7396-7404, 2018; PubMed: 29741655; DOI: 10.1093/nar/gky345

Experimental method

X-RAY DIFFRACTION (1.58 Å)