5YQZ

Structure of the glucagon receptor in complex with a glucagon analogue

Summary for 5YQZ

• Entry DOI: 10.2210/pdb5yqz/pdb
• Descriptor: Glucagon receptor,Endolysin,Glucagon receptor, Glucagon analogue, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: human gcgr receptor, class b, 7tm domain, membrane, lcp, xfel, signaling protein, signaling protein-hydrolase complex, signaling protein/hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cell membrane ; Multi-pass membrane protein : P47871
• Total number of polymer chains: 2
• Total formula weight: 72227.75

Authors

Zhang, H.,Qiao, A.,Yang, L.,VAN EPS, N.,Frederiksen, K.,Yang, D.,Dai, A.,Cai, X.,Zhang, H.,Yi, C.,Can, C.,He, L.,Yang, H.,Lau, J.,Ernst, O.,Hanson, M.,Stevens, R.,Wang, M.,Seedtz-Runge, S.,Jiang, H.,Zhao, Q.,Wu, B. (deposition date: 2017-11-08, release date: 2018-01-17, Last modification date: 2023-11-22)

• Primary citation: Zhang, H.,Qiao, A.,Yang, L.,Van Eps, N.,Frederiksen, K.S.,Yang, D.,Dai, A.,Cai, X.,Zhang, H.,Yi, C.,Cao, C.,He, L.,Yang, H.,Lau, J.,Ernst, O.P.,Hanson, M.A.,Stevens, R.C.,Wang, M.W.,Reedtz-Runge, S.,Jiang, H.,Zhao, Q.,Wu, B.; Structure of the glucagon receptor in complex with a glucagon analogue.; Nature, 553:106-110, 2018; PubMed: 29300013; DOI: 10.1038/nature25153

Experimental method

X-RAY DIFFRACTION (3 Å)