5YQB
Crystal structure of E.coli aminopeptidase N in complex with Puromycin
Summary for 5YQB
Entry DOI | 10.2210/pdb5yqb/pdb |
Descriptor | Aminopeptidase N, ZINC ION, O-methyl-L-tyrosine, ... (6 entities in total) |
Functional Keywords | puromycin, m1 class aminopeptidase, hydrolase |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 101978.24 |
Authors | Marapaka, A.K.,Ganji, R.J.,Reddi, R.,Addlagatta, A. (deposition date: 2017-11-06, release date: 2018-11-14, Last modification date: 2023-11-22) |
Primary citation | Reddi, R.,Ganji, R.J.,Marapaka, A.K.,Bala, S.C.,Yerra, N.V.,Haque, N.,Addlagatta, A. Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis Int.J.Biol.Macromol., 165:1373-1381, 2020 Cited by DOI: 10.1016/j.ijbiomac.2020.10.035PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
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