5YOD

Crystal structure of zika virus NS3 protease in complex with a small molecule inhibitor

Summary for 5YOD

• Entry DOI: 10.2210/pdb5yod/pdb
• Descriptor: NS2B cofactor, NS3 protease, BENZOIC ACID, ... (4 entities in total)
• Functional Keywords: non-structural protein 3, serine protease, zika viral protease, viral protein-inhibitor complex, viral protein/inhibitor
• Biological source: Zika virus; More
• Total number of polymer chains: 8
• Total formula weight: 100036.13

Authors

Phoo, W.W.,Zhang, Z.Z. (deposition date: 2017-10-27, release date: 2018-03-21, Last modification date: 2023-11-22)

• Primary citation: Li, Y.,Zhang, Z.,Phoo, W.W.,Loh, Y.R.,Li, R.,Yang, H.Y.,Jansson, A.E.,Hill, J.,Keller, T.H.,Nacro, K.,Luo, D.,Kang, C.; Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor; Structure, 26:555-564.e3, 2018; PubMed: 29526431; DOI: 10.1016/j.str.2018.02.005

Experimental method

X-RAY DIFFRACTION (1.9 Å)