5YO1
Structure of ePepN E298A mutant in complex with Puromycin
Summary for 5YO1
Entry DOI | 10.2210/pdb5yo1/pdb |
Descriptor | Aminopeptidase N, ZINC ION, PUROMYCIN, ... (6 entities in total) |
Functional Keywords | m1 class aminopeptidase, hydrolase |
Biological source | Escherichia coli K12 |
Total number of polymer chains | 1 |
Total formula weight | 103519.70 |
Authors | Ganji, R.J.,Reddi, R.,Marapaka, A.K.,Addlagatta, A. (deposition date: 2017-10-26, release date: 2018-11-07, Last modification date: 2023-11-22) |
Primary citation | Reddi, R.,Ganji, R.J.,Marapaka, A.K.,Bala, S.C.,Yerra, N.V.,Haque, N.,Addlagatta, A. Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis Int.J.Biol.Macromol., 165:1373-1381, 2020 Cited by DOI: 10.1016/j.ijbiomac.2020.10.035PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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