5YDR
Structure of DNMT1 RFTS domain in complex with ubiquitin
Summary for 5YDR
Entry DOI | 10.2210/pdb5ydr/pdb |
Descriptor | Polyubiquitin-B, DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, ... (5 entities in total) |
Functional Keywords | dna methylation, protein binding, protein binding-transferase complex, protein binding/transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus : P26358 |
Total number of polymer chains | 3 |
Total formula weight | 45239.20 |
Authors | Qian, C. (deposition date: 2017-09-14, release date: 2018-02-21, Last modification date: 2023-11-22) |
Primary citation | Li, T.,Wang, L.,Du, Y.,Xie, S.,Yang, X.,Lian, F.,Zhou, Z.,Qian, C. Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation. Nucleic Acids Res., 46:3218-3231, 2018 Cited by PubMed: 29471350DOI: 10.1093/nar/gky104 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.003 Å) |
Structure validation
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