5YDR

Structure of DNMT1 RFTS domain in complex with ubiquitin

5YDR の概要

• エントリーDOI: 10.2210/pdb5ydr/pdb
• 分子名称: Polyubiquitin-B, DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, ... (5 entities in total)
• 機能のキーワード: dna methylation, protein binding, protein binding-transferase complex, protein binding/transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Nucleus : P26358
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45239.20

構造登録者

Qian, C. (登録日: 2017-09-14, 公開日: 2018-02-21, 最終更新日: 2023-11-22)

• 主引用文献: Li, T.,Wang, L.,Du, Y.,Xie, S.,Yang, X.,Lian, F.,Zhou, Z.,Qian, C.; Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.; Nucleic Acids Res., 46:3218-3231, 2018; PubMed: 29471350; DOI: 10.1093/nar/gky104

実験手法

X-RAY DIFFRACTION (2.003 Å)