5YAV
Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction
Summary for 5YAV
Entry DOI | 10.2210/pdb5yav/pdb |
Descriptor | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta, 1-phenyl-5-propan-2-ylsulfanyl-1,2,3,4-tetrazole (3 entities in total) |
Functional Keywords | pde6delta, oncoprotein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 17661.28 |
Authors | Bing, X.,Yanlian, L.,Danyan, C. (deposition date: 2017-09-01, release date: 2018-09-05, Last modification date: 2024-03-27) |
Primary citation | Bing, X.,Yanlian, L.,Danyan, C. Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.989 Å) |
Structure validation
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