5YAV
Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | polymer | 150 | 17441.0 | 1 | UniProt (O43924) Pfam (PF05351) In PDB | Homo sapiens (Human) | GMP-PDE delta,Protein p17 |
2 | B | 1-phenyl-5-propan-2-ylsulfanyl-1,2,3,4-tetrazole | non-polymer | 220.3 | 1 | Chemie (8SF) | |||
3 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 17441.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 220.3 | |
All* | Total formula weight | 17661.3 |