5YAV
Fragment-based Drug Discovery of inhibitors to block PDEdelta-RAS protein-protein interaction
Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0005095 | molecular_function | GTPase inhibitor activity |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0005856 | cellular_component | cytoskeleton |
B | 0005929 | cellular_component | cilium |
B | 0007601 | biological_process | visual perception |
B | 0016020 | cellular_component | membrane |
B | 0030659 | cellular_component | cytoplasmic vesicle membrane |
B | 0031267 | molecular_function | small GTPase binding |
B | 0031410 | cellular_component | cytoplasmic vesicle |
B | 0042995 | cellular_component | cell projection |
B | 0050953 | biological_process | sensory perception of light stimulus |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | binding site for residue 8SF B 201 |
Chain | Residue |
B | LEU22 |
B | TRP32 |
B | LEU38 |
B | ALA47 |
B | ARG61 |
B | GLN78 |
B | THR131 |
B | LEU147 |