5Y7X

Human Peroxisome proliferator-activated receptor (PPAR) delta in complexed with a potent and selective agonist

5Y7X の概要

• エントリーDOI: 10.2210/pdb5y7x/pdb
• 分子名称: Peroxisome proliferator-activated receptor delta, 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-selenazol-5-yl]methylsulfanyl]phenoxy]ethanoic acid, POTASSIUM ION, ... (7 entities in total)
• 機能のキーワード: peroxisome proliferator-activated receptor, selenazole, diabetes, pi-sulfur interaction., protein binding
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 68354.75

構造登録者

Kim, H.L.,Chin, J.W.,Cho, S.J.,Song, J.Y.,Yoon, H.S.,Bae, J.H. (登録日: 2017-08-18, 公開日: 2018-08-01, 最終更新日: 2023-11-22)

• 主引用文献: Chin, J.W.,Cho, S.J.; Design, synthesis, and the X-ray co-crystal structure of Highly Potent, Selective, and Orally Bioavailable, Novel Peroxisome Proliferator-Activated Receptor delta Agonists; To Be Published,

実験手法

X-RAY DIFFRACTION (1.699 Å)