5Y66

Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN and Ro61-8048

5Y66 の概要

• エントリーDOI: 10.2210/pdb5y66/pdb
• 分子名称: Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, ... (5 entities in total)
• 機能のキーワード: kmo, inhibitor, l-kyn, ro 61-8048, oxidoreductase
• 由来する生物種: Pseudomonas fluorescens
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 53528.28

構造登録者

Xiang, Y.,Gao, J.J.,Zhu, D.Y. (登録日: 2017-08-10, 公開日: 2017-12-27, 最終更新日: 2024-03-27)

• 主引用文献: Gao, J.,Yao, L.,Xia, T.,Liao, X.,Zhu, D.,Xiang, Y.; Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048; FASEB J., 32:2036-2045, 2018; PubMed: 29208702; DOI: 10.1096/fj.201700397RR

実験手法

X-RAY DIFFRACTION (2.34 Å)