5Y52
Crystal Structure of Highly Active BTUO Mutant P287G Improved by Humidity Control at 83% RH
Summary for 5Y52
Entry DOI | 10.2210/pdb5y52/pdb |
Descriptor | Uric acid degradation bifunctional protein, 8-AZAXANTHINE, OXYGEN MOLECULE, ... (6 entities in total) |
Functional Keywords | protein engineering, oxidase, ph dependence, enzyme activation, flexibility, loop plasticity, oxidoreductase |
Biological source | Bacillus sp. (strain TB-90) |
Total number of polymer chains | 4 |
Total formula weight | 153093.61 |
Authors | Itoh, T.,Kishimoto, T.,Nishiya, Y. (deposition date: 2017-08-07, release date: 2018-08-08, Last modification date: 2023-11-22) |
Primary citation | Hibi, T.,Itoh, T.,Fukada, H.,Kishimoto, T.,Nishiya, Y. Conformational Flexibility of Plastic Interface Loop Allows Entropic Adaptation of Urate Oxidase to Environmental pH To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.63 Å) |
Structure validation
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