5XZW

Crystal structure of Rad53 1-466

Summary for 5XZW

DescriptorSerine/threonine-protein kinase RAD53 (2 entities in total)
Functional Keywordsserine/threonine-protein kinase, fha domain, checkpoint kinase, transferase
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Cellular locationNucleus  P22216
Total number of polymer chains2
Total molecular weight105012.94
Authors
Weng, J.H.,Tsai, M.D. (deposition date: 2017-07-14, release date: 2017-10-11)
Primary citation
Chen, E.S.,Weng, J.H.,Chen, Y.H.,Wang, S.C.,Liu, X.X.,Huang, W.C.,Matsui, T.,Kawano, Y.,Liao, J.H.,Lim, L.H.,Bessho, Y.,Huang, K.F.,Wu, W.J.,Tsai, M.D.
Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation
Biochemistry, 56:5112-5124, 2017
PubMed: 28858528 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.7b00689
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.281190.4%3.7%9.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 5xzw
no rotation
Molmil generated image of 5xzw
rotated about x axis by 90°
Molmil generated image of 5xzw
rotated about y axis by 90°