Crystal structure of Rad53 1-466 in complex with AMP-PNP

Summary for 5XZV

DescriptorSerine/threonine-protein kinase RAD53, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (2 entities in total)
Functional Keywordsserine/threonine-protein kinase, fha domain, checkpoint kinase, transferase
Biological sourceSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Cellular locationNucleus  P22216
Total number of polymer chains2
Total molecular weight106025.33
Weng, J.H.,Tsai, M.D. (deposition date: 2017-07-14, release date: 2017-10-11)
Primary citation
Chen, E.S.,Weng, J.H.,Chen, Y.H.,Wang, S.C.,Liu, X.X.,Huang, W.C.,Matsui, T.,Kawano, Y.,Liao, J.H.,Lim, L.H.,Bessho, Y.,Huang, K.F.,Wu, W.J.,Tsai, M.D.
Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation
Biochemistry, 56:5112-5124, 2017
PubMed: 28858528 (PDB entries with the same primary citation)
DOI: 10.1021/acs.biochem.7b00689
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2902405.5%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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