5XRD

Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FS7

Summary for 5XRD

• Entry DOI: 10.2210/pdb5xrd/pdb
• Descriptor: Heat shock protein HSP 90-alpha, N-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(4-methoxyphenyl)-1H-pyrazol-5-yl}acetamide (3 entities in total)
• Functional Keywords: heat shock protein hsp 90, inhibitor, complex, chaperone
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 26038.19

Authors

Li, J.,Shi, F.,Xiong, B.,He, J.H. (deposition date: 2017-06-08, release date: 2019-05-22, Last modification date: 2023-11-22)

• Primary citation: Li, J.,Shi, F.,Xiong, B.,He, J.H.; Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FS7; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.3 Å)