5XRD
Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FS7
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock protein HSP 90-alpha | polymer | 228 | 25656.8 | 1 | UniProt (P07900) Pfam (PF13589) | Homo sapiens (Human) | Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
| 2 | B (A) | N-{3-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(4-methoxyphenyl)-1H-pyrazol-5-yl}acetamide | non-polymer | 381.4 | 1 | Chemie (9ZC) | |||
| 3 | C (A) | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25656.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 381.4 | |
| All* | Total formula weight | 26038.2 |
