5XKH

Crystal structure of T2R-TTL-CF1 complex

Summary for 5XKH

• Entry DOI: 10.2210/pdb5xkh/pdb
• Descriptor: Tubulin alpha-1B chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[(4-methoxy-3-oxidanyl-phenyl)-methyl-amino]chromen-2-one, ... (12 entities in total)
• Functional Keywords: colchicine binding domain, tubulin inhibitor, tublin, structural protein
• Biological source: Sus scrofa (Pig); More
• Total number of polymer chains: 6
• Total formula weight: 264703.38

Authors

Wang, Y.,Yang, J.,Wang, T.,Chen, L. (deposition date: 2017-05-07, release date: 2018-06-20, Last modification date: 2024-03-27)

• Primary citation: Yan, W.,Yang, J.; Identification of a powerful and reversible microtubule-inhibitor with efficacy against multidrug-resistant tumors; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)