5XKH

Crystal structure of T2R-TTL-CF1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Tubulin alpha-1B chain	polymer	451	50204.4	2	UniProt (Q2XVP4) Pfam (PF00091) Pfam (PF03953)	Sus scrofa (Pig)	Alpha-tubulin ubiquitous,Tubulin K-alpha-1,Tubulin alpha-ubiquitous chain
2	B, D (B, D)	Tubulin beta chain	polymer	445	49999.9	2	UniProt (F2Z5B2) Pfam (PF00091) Pfam (PF03953) UniProt (by SIFTS) (P02554)	Sus scrofa (Pig)
3	E (E)	Stathmin-4	polymer	143	16844.2	1	UniProt (P63043) Pfam (PF00836)	Rattus norvegicus (Rat)	Stathmin-like protein B3,RB3
4	F (F)	Uncharacterized protein	polymer	384	44378.5	1	UniProt (E1BQ43)	Gallus gallus (Chicken)
5	G, O, S (A, C, D)	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	3	Chemie (GTP)
6	H, L, P, T (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
7	I, Q (A, C)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
8	J (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
9	K (B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
10	M (B)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
11	N, R (B, C)	4-[(4-methoxy-3-oxidanyl-phenyl)-methyl-amino]chromen-2-one	non-polymer		297.3	2	Chemie (89C)
12	U, V, W, X, Y... (A, B, C, D, E...)	water	water		18.0	664	Chemie (HOH)

Sequence modifications

B, D: 1 - 445 (UniProt: F2Z5B2)

PDB	External Database	Details
Gly 440	Glu 440	conflict
Glu 441	Gly 441	conflict

E: 5 - 145 (UniProt: P63043)

PDB	External Database	Details
Met 3	-	expression tag
Ala 4	-	expression tag

F: 1 - 378 (UniProt: E1BQ43)

PDB	External Database	Details
His 379	-	expression tag
His 380	-	expression tag
His 381	-	expression tag
His 382	-	expression tag
His 383	-	expression tag
His 384	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	261631.3
Non-Polymers*	Number of molecules	14
	Total formula weight	3072.1
All*	Total formula weight	264703.4

*Water molecules are not included.