5XHR
Crystal structure of P99 beta-lactamase in complex with a penicillin derivative MPC-1
Summary for 5XHR
Entry DOI | 10.2210/pdb5xhr/pdb |
Descriptor | Beta-lactamase, (2~{R},4~{S})-5,5-dimethyl-2-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-5-thiophen-2-yl-pentan-2-yl]-1,3-thiazolidine-4-carboxylic acid (3 entities in total) |
Functional Keywords | hydrolase |
Biological source | Enterobacter cloacae |
Cellular location | Periplasm : P05364 |
Total number of polymer chains | 1 |
Total formula weight | 39911.52 |
Authors | |
Primary citation | Pan, X.,He, Y.,Chen, T.,Chan, K.F.,Zhao, Y. Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C beta-Lactamases Antimicrob. Agents Chemother., 61:-, 2017 Cited by PubMed: 28971874DOI: 10.1128/AAC.01288-17 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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