5XHG

Crystal structure of Trastuzumab Fab fragment bearing Ne-(o-azidobenzyloxycarbonyl)-L-lysine

Summary for 5XHG

Entry DOI	10.2210/pdb5xhg/pdb
Descriptor	polypeptide(L), polypeptide(H), (2-azidophenyl)methyl hydrogen carbonate, ... (7 entities in total)
Functional Keywords	fab, immune system
Biological source	MUS MUSCULUS (MOUSE) More
Total number of polymer chains	4
Total formula weight	95036.72
Authors	Kuratani, M.,Yanagisawa, T.,Sakamoto, K.,Yokoyama, S. (deposition date: 2017-04-20, release date: 2017-12-20, Last modification date: 2019-12-25)
Primary citation	Kato, A.,Kuratani, M.,Yanagisawa, T.,Ohtake, K.,Hayashi, A.,Amano, Y.,Kimura, K.,Yokoyama, S.,Sakamoto, K.,Shiraishi, Y. Extensive Survey of Antibody Invariant Positions for Efficient Chemical Conjugation Using Expanded Genetic Codes. Bioconjug. Chem., 28:2099-2108, 2017 Cited by PubMed: 28727448 DOI: 10.1021/acs.bioconjchem.7b00265 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation