5XHE

Crystal structure analysis of the second bromodomain of BRD2 covalently linked to b-mercaptoethanol

5XHE の概要

• エントリーDOI: 10.2210/pdb5xhe/pdb
• 関連するPDBエントリー: 5XHK
• 分子名称: Bromodomain-containing protein 2, TRIETHYLENE GLYCOL, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: bet family, brd2, bromodomain, b-mercaptoethanol, cme, transcription
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 13882.92

構造登録者

Padmanabhan, B.,Mathur, S.,Tripathi, S.K.,Deshmukh, P. (登録日: 2017-04-20, 公開日: 2017-09-06, 最終更新日: 2018-08-01)

• 主引用文献: Mathur, S.,Deshmukh, P.,Tripathi, S.,Marimuthu, P.,Padmanabhan, B.; Insights into the crystal structure of BRD2-BD2 - phenanthridinone complex and theoretical studies on phenanthridinone analogs.; J. Biomol. Struct. Dyn., 36:2342-2360, 2018; PubMed: 28696179; DOI: 10.1080/07391102.2017.1353441

実験手法

X-RAY DIFFRACTION (1.4 Å)