5XHE
Crystal structure analysis of the second bromodomain of BRD2 covalently linked to b-mercaptoethanol
Summary for 5XHE
Entry DOI | 10.2210/pdb5xhe/pdb |
Related | 5XHK |
Descriptor | Bromodomain-containing protein 2, TRIETHYLENE GLYCOL, GLYCEROL, ... (4 entities in total) |
Functional Keywords | bet family, brd2, bromodomain, b-mercaptoethanol, cme, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 13882.92 |
Authors | Padmanabhan, B.,Mathur, S.,Tripathi, S.K.,Deshmukh, P. (deposition date: 2017-04-20, release date: 2017-09-06, Last modification date: 2018-08-01) |
Primary citation | Mathur, S.,Deshmukh, P.,Tripathi, S.,Marimuthu, P.,Padmanabhan, B. Insights into the crystal structure of BRD2-BD2 - phenanthridinone complex and theoretical studies on phenanthridinone analogs. J. Biomol. Struct. Dyn., 36:2342-2360, 2018 Cited by PubMed: 28696179DOI: 10.1080/07391102.2017.1353441 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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