5XDS

Crystal structure of Mycobacterium tuberculosis HisB bound with an inhibitor

5XDS の概要

• エントリーDOI: 10.2210/pdb5xds/pdb
• 分子名称: Imidazoleglycerol-phosphate dehydratase, MANGANESE (II) ION, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: mycobacterium tuberculosis, tuberculosis, imidazoleglycerol phosphate dehydratase, drug target, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• 細胞内の位置: Cytoplasm : P9WML9
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23934.99

構造登録者

Kumar, D.,Jha, B.,Ahangar, M.S.,Kumar, B.B. (登録日: 2017-03-29, 公開日: 2018-04-04, 最終更新日: 2023-11-22)

• 主引用文献: Kumar, D.,Jha, B.,Bhatia, I.,Ashraf, A.,Dwivedy, A.,Biswal, B.K.; Characterization of a triazole scaffold compound as an inhibitor of Mycobacterium tuberculosis imidazoleglycerol-phosphate dehydratase.; Proteins, 2021; PubMed: 34288118; DOI: 10.1002/prot.26181

実験手法

X-RAY DIFFRACTION (1.75 Å)