5XC6
Dengue Virus 4 NS3 Helicase in complex with SSRNA SLA12
Summary for 5XC6
Entry DOI | 10.2210/pdb5xc6/pdb |
Related | 5XC7 |
Descriptor | NS3 Helicase, RNA (5'-R(*AP*GP*UP*UP*GP*UP*UP*AP*GP*UP*CP*U)-3'), PHOSPHATE ION (3 entities in total) |
Functional Keywords | helicase, dengue ns3, rna, hydrolase, hydrolase-rna complex, hydrolase/rna |
Biological source | Dengue virus 4 More |
Cellular location | Host endoplasmic reticulum membrane ; Peripheral membrane protein ; Lumenal side . Host nucleus . Secreted . Virion membrane ; Multi-pass membrane protein : M9P7S0 |
Total number of polymer chains | 4 |
Total formula weight | 110503.49 |
Authors | Swarbrick, C.M.D.,Basavannacharya, C.,Chan, K.W.K.,Chan, S.A.,Singh, D.,Wei, N.,Phoo, W.W.,Luo, D.,Lescar, J.,Vasudevan, S.G. (deposition date: 2017-03-22, release date: 2017-11-08, Last modification date: 2023-11-22) |
Primary citation | Swarbrick, C.M.D.,Basavannacharya, C.,Chan, K.W.K.,Chan, S.A.,Singh, D.,Wei, N.,Phoo, W.W.,Luo, D.,Lescar, J.,Vasudevan, S.G. NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication Nucleic Acids Res., 45:12904-12920, 2017 Cited by PubMed: 29165589DOI: 10.1093/nar/gkx1127 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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